Science, app and laboratory: Apolipoprotein B

  1. What we test
  2. Heart and vessels
  3. Apolipoprotein B
  4. Science, app and laboratory

04 · Why it matters

Why Apolipoprotein B matters.What the science says, in three ideas.

  1. 01

    It counts particles, not just cholesterol

    VLDL, IDL, LDL and Lp(a) each carry a single ApoB. So your ApoB equals the total number of those particles.1

  2. 02

    What matters is how many there are

    Cholesterol only enters the wall of your arteries inside these particles. The more that circulate, the more can stay there. The cholesterol each one carries varies.1

  3. 03

    European guidelines use it

    The ESC and EAS lipid guidelines consider it useful for assessing cardiovascular risk, above all with high triglycerides, diabetes or obesity.2

05 · In the app

This is how you will see your Apolipoprotein B.Three screens, step by step.

How it works
  1. Data screen of the Santé app with the biomarker list in the optimal range

    Your results

    You see every value with its status. Tap ApoB to open it.

  2. ApoB detail screen in the Santé app: 0.82 g/L, in the optimal range

    Your ApoB

    Your value, its optimal range and how it has moved since your last blood test.

  3. Action plan screen of the Santé app with steps to keep ApoB in range

    Your plan

    Clear steps to keep it there. And Santé AI for your questions.

Real app screens with example values. Santé AI does not diagnose. If this is an emergency, call 112.

06 · Compared with

Apolipoprotein B against other markers.What each one counts and what it misses.

See the catalogue
MarkerWhat it measuresWhat it addsWhat it misses
ApoBThe number of particles that carry cholesterol to your arteries.A single figure that counts them all, VLDL and Lp(a) included.It does not say how much cholesterol each particle carries.
LDL cholesterolThe cholesterol inside LDL particles.The most used figure, and the one with the most studies behind it.If your particles are small, it can undercount how many there are.
Non-HDL cholesterolAll your cholesterol minus HDL.It includes VLDL and remnants. It is calculated without fasting.It still measures cholesterol, not particles.
Lp(a)One specific particle type that carries ApoB, largely inherited.Guidelines advise measuring it at least once in a lifetime.Your habits barely change it.
ApoB/ApoA1 ratioThe balance between ApoB particles and HDL.It sums the balance up in one number.It is always read with the rest of your lipids.

We measure all five in your yearly blood test. Your clinician reads them together.1, 2

07 · How we measure it

In the laboratory.Your sample never leaves Barcelona.

Meet the laboratory
A sample tube with a green cap next to a gauze and a plaster
One blood draw
Sample
Blood (serum).
Analyzer
Our biochemistry analyser.
Where
Santé Labs, Barcelona. The same day.
Unit
g/L.
Fasting
ApoB does not need it.1 We ask you for 10–12 hours for other markers in your blood test.

08 · What can influence it

What moves it.Four factors, without doses or recipes.

Food

What you eat, above all fats.

Physical activity

Moving every day and training.

Genetics

Your family history counts.

Medication

Some medicines change it.

Your clinician reads your value alongside these factors and leaves you a note. Your action plan takes them into account. And you can ask Santé AI anything about your result.

09 · Related

Related markers.They are read together with Apolipoprotein B.

See the catalogue
BiomarkerWhat it shows

10 · Sources

  1. Sniderman AD, Thanassoulis G, Glavinovic T, et al. Apolipoprotein B particles and cardiovascular disease: a narrative review. JAMA Cardiology. 2019;4(12):1287–1295. doi:10.1001/jamacardio.2019.3780
  2. Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias. European Heart Journal. 2020;41(1):111–188. doi:10.1093/eurheartj/ehz455
  3. Lab Tests Online UK. Apolipoprotein B. Reviewed in 2024. labtestsonline.org.uk
  4. Clinical and Laboratory Standards Institute. EP28-A3c: Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory. 3rd ed. CLSI; 2010.

This content is educational and does not replace an assessment by a health professional. It does not diagnose.

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